Contrave combines two drugs currently on the market: the antidepressant bupropion (Wellbutrin) and the antidepressant drug naltrexone. The new drug will contain a warning box because it contains bupropion, which warns- doctors and patients about the increased risk of suicidal ideation with antidepressants.
Although weight-loss experts believe that all three drugs work- in the same way, Contrave is a good supplement because not all weight loss drugs have the same effect on everyone.
Contrave (naltrexone/bupropion) is a medicine that combines two medicines. Bupropion is an inhibitor of dopamine and norepinephrine reuptake, and naltrexone is an opioid antagonist. To reduce the need to eat, they work together in the areas of your brain that are responsible for regulating appetite and reward systems.